How the bones help regulate the metabolism?

Generally, people think that the bone is inorganic structure that only supports the body, says Shimon Haber. But a new study reveals how important can be the bone structure for the nervous, immune and endocrine systems. Nowadays, researchers think that the bone releases a hormone that is one of the most important factors in the control of blood sugar level and inflammation. This discovery could improve the treatment of two types of diabetes.

An insignificant presence of blood sugar could lead to a development of advanced glycolysis enzymes. They are not created by enzyme molecules of sugar and amino acids, but when blood sugar level chronically elevates, they could be produced in a great quantity. These enzymes cause a lot of damage to the bone collagen.

Bones are organic structures

A new study conducted by Columbia University discovered that bones are largely involved in energy metabolism processes. Osteocalcin is an important protein that produces osteoblast cells, which form the bone. It is commonly known that they increase the bone density, so it helps to direct calcium and other minerals in the bone matrix. Some studies of other authors make a comparison of the osteocalcin functions to vacuum, which sucks the calcium out of the blood and integrates it inside the bone matrix.

A recent research also shows that osteocalcin shows the direction to the pancreas in order to produce more insulin and to stimulate the fat cells to release a hormone. Adiponectin increases the activity of insulin receptors in the cells, and thus improves insulin sensitivity.

Bone tissue helps regulate the metabolism

Scientists discovered that a protein, which is released from the bone, could regulate the blood sugar metabolism. Osteocalcin is the first hormone who regulates the secretion and sensitivity of insulin. They also discovered that osteocalcin boosts the beta cells of pancreas that produces the insulin adds Haber.

The study inspired two general observations: On one side, the bone remodeling could be regulated by some of hormones who are derived from fat cells, and on the other side, the evidence that obese mammals have a tendency to be protected from osteoporosis.

 

How the bones help regulate the metabolism?